Mice study identifies pathways that link high-fat diet to atherosclerosis

It's long been known that a high-fat diet can lead to clogged arteries, but we have only recently begun to learn in detail how the process works. A new study in experimental mice could go a long way to finding treatments to keep arteries open and flowing.

In a study published this month in JACC Basic To Translational Science, researchers from Tokyo Medical and Dental University (TMDU) have continued their research into how a high-fat diet causes atherosclerosis, the fatty buildup of plaques on the walls of blood vessels that can lead to heart attacks and other vascular disease. Atherosclerosis is not as simple as fats getting stuck in your arteries--it's actually an inflammatory disease driven by the body's own immune response, particularly neutrophils, the white blood cells that attack infections and respond to injuries.
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