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- Once mRNA is in the cytoplasm, translation occurs. This is the process where the genetic information
- stored in mRNA molecules is converted to proteins. This happens with the help of ribosomes. Ribosomes,
- which are made from rRNA, or ribosomal RNA, are organelles that make proteins. During translation, the
- mRNA attaches itself to the ribosome, which reads the genetic information in the nucleotide sequence.
- The genetic information is used to make protein molecules with specific sequences of amino acids. Each
- gene includes the exact number of codons to make a specific type of protein, and each mRNA codon has
- instructions for a different amino acid to be added to the protein. The ribosome reads the codons in order
- from the mRNA, and tRNA, or transfer RNA, finds the correct amino acid. Since there are twenty different
- amino acids, each one is retrieved by a slightly different form of tRNA molecule. tRNA molecules are
- folded in such a way that one end can recognize and attach to a specific amino acid, while the other end
- forms an anticodon. The anticodon contains complementary base pairs for the codons in the mRNA
- strand. When the correct anticodon recognizes and binds to the codon, the tRNA transfers the amino acid
- to the ribosome. Peptide bonds form between adjacent amino acids, binding them to the polypeptide
- chain. When the entire mRNA strand has been read, and the correct amino acids have been added, the
- protein is finished. Once protein synthesis is complete, the mRNA strand is destroyed and its constituent
- parts recycled.
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