Flesh pokey resistant to drugs

“Anesthetic...sleep aid... Ahh, a muscle relaxant!” cried the Jeff R. The fingers
on his right hand had become hypodermic needles, and he was throwing every type of
medication he had at those walls. ...But nothing seemed to have any effect at all.
“...Well, I may as well try this one–strong laxative...!”

Grumble-grumble-grumble! Terrifying vibrations coursed through those walls,
but other than that, nothing happened.

- Mother 2, Chapter 9 pg. 159