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Sterilization in males is typically achieved through a surgical procedure called a vasectomy, which involves cutting or sealing the vas deferens to prevent sperm from mixing with semen - Harvard Health](https://www.health.harvard.edu/birth-control/methods/type/sterilization-men). However, there are some chemicals that have been researched for their potential to induce sterility:

1. Gossypol: A compound derived from cottonseed oil, which has been studied for its ability to reduce sperm production.
2. RISUG (Reversible Inhibition of Sperm Under Guidance): A polymer gel injected into the vas deferens that blocks sperm.
3. Hormonal Methods: Combinations of testosterone and progestin have been researched to suppress sperm production.

These methods are still under research and are not as widely used or accepted as surgical sterilization - Wikipedia](https://en.wikipedia.org/wiki/Sterilization_%28medicine%29).