One dose of Pfizer vaccine generates strong immune response against COVID-19

A new study led by the Universities of Sheffield and Oxford with support from the UK Coronavirus Immunology Consortium (UK-CIC) has found that 99 per cent of people generate a robust immune response against Covid-19 after just one dose of the Pfizer vaccine.

The Protective Immunity from T cells to Covid-19 in Health workers study (PITCH) examined how the immune system responds to Covid-19 after one dose of the Pfizer vaccine among people who have been infected by Covid-19 before and those who have not.

It suggests one dose of the vaccine protects against severe disease, supporting the decision to delay the second dose and provide protection to as many higher-risk groups as possible by providing more first doses. The study showed after two doses levels of protection were even stronger, underlining the importance of people coming forward for their second dose.
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