Enable/Disable NTFS file compression programmatically

import win32file
import winioctlcon
import win32con
import struct

def set_file_compression(filename, state):
    handle = win32file.CreateFile(filename
        , win32file.GENERIC_READ | win32file.GENERIC_WRITE
        , 0, None
        , win32file.OPEN_EXISTING
        , 0, None)
    if state:
        buffer = struct.pack('H', win32con.COMPRESSION_FORMAT_DEFAULT)
    else:
        buffer = struct.pack('H', win32con.COMPRESSION_FORMAT_NONE)

    win32file.DeviceIoControl(Device = handle
        , IoControlCode = winioctlcon.FSCTL_SET_COMPRESSION
        , InBuffer = buffer
        , OutBuffer = None)

    win32file.CloseHandle(handle)

set_file_compression('test.dat', False)