1?

from tkinter import *

root = Tk()
root.title("Hihihanki-hahanki")
root.geometry("350x400")

button_x1_y1 = Button(text="button1")
button_x1_y1.grid(row=0, column=0, columnspan=2, ipadx=70, ipady=6, padx=70, pady=10)

button_x1_y2 = Button(text="button3")
button_x1_y2.grid(row=1, column=0, ipadx=6, ipady=6, padx=5, pady=5)

button_x1_y3 = Button(text="button4")
button_x1_y3.grid(row=1, column=1, ipadx=6,  ipady=6, padx=5, pady=5)




root.mainloop()