export const markupGreeterMessage = new Menu('markupGreeterMessage');

 const notifications = new Set<number>();

    function toggleNotifications(id: number) {
      if (!notifications.delete(id)) notifications.add(id);
    }

    markupGreeterMessage.text(
      (ctx) => (ctx.from && notifications.has(ctx.from.id) ? '🔔' : '🔕'),
      (ctx) => {
        toggleNotifications(ctx.from.id);
        ctx.menu.update();
      }
    );

 const greeterMessage = `...`;

      ...
      await <save DB>.then(
        async () =>
          await ctx.reply(greeterMessage, {
            reply_markup: markupGreeterMessage,
          })
      );